You’ve probably heard of baking soda being used for heartburn or even cleaning, but did you know it might actually help with autoimmune diseases like rheumatoid arthritis? It sounds surprising, right? But recent research suggests that something as simple as a daily dose of baking soda could help reduce inflammation in people dealing with these conditions.
Autoimmune diseases, like rheumatoid arthritis, cause the immune system to go into overdrive, attacking healthy parts of the body—leading to painful inflammation, especially in the joints. But here’s the exciting part: a study from the Medical College of Georgia found that baking soda can signal the immune system to calm down and stop its aggressive attacks.
This could mean that an affordable and natural remedy sitting in your kitchen cupboard might actually help ease the discomfort of autoimmune diseases. Sounds pretty amazing, doesn’t it?

How Baking Soda Calms the Immune System
So, how exactly does baking soda work its magic? It all comes down to the immune system and the signals it receives. When you drink a solution of baking soda, it sends a message to special cells in the body called mesothelial cells. These cells line your internal organs and help them function smoothly without sticking together. But they do something else, too—they communicate with your immune system.
In autoimmune diseases like rheumatoid arthritis, the immune system tends to get overzealous, attacking healthy tissues as if they were harmful invaders. This leads to inflammation and pain. But when baking soda enters the mix, it prompts the mesothelial cells to tell the immune system to take a step back. Instead of launching an aggressive attack, the immune system relaxes, reducing inflammation and the uncomfortable symptoms that come with it.
Researchers believe this calming effect could be a game-changer for people struggling with chronic autoimmune conditions.
The Role of Mesothelial Cells: Your Body’s Hidden Communicators
Mesothelial cells are found lining your organs, helping everything function smoothly without sticking together. But here’s something cool: they don’t just sit there—they send signals to your immune system. When you drink baking soda, these cells start communicating with the spleen, which helps control immune reactions.
In autoimmune diseases, the spleen often overreacts, producing too many inflammatory cells that end up attacking healthy tissues. Baking soda helps stop this process by telling the mesothelial cells to calm the spleen down. This way, the spleen creates fewer of these aggressive cells, helping reduce inflammation and pain.
Baking Soda’s Effect on Inflammation: More Than Just the Spleen
While the spleen plays a big role in managing inflammation, baking soda’s benefits don’t stop there. Research has shown that it can also influence other parts of the body, like the kidneys and the blood. In fact, baking soda has been used in treatments for chronic kidney disease because it helps reduce inflammation in the kidneys.
In one study, both rats with kidney disease and healthy rats showed a similar response: baking soda lowered the number of pro-inflammatory cells (which cause damage) and increased anti-inflammatory cells (which help with healing). This shift suggests that baking soda has a powerful effect on calming the body’s inflammatory response—not just in one organ but across multiple systems.
When the researchers tested it on healthy people, they saw the same thing happening in the blood. This means the shift from inflammation to healing was happening throughout the body, showing that baking soda’s effect is widespread and potentially useful for many different health conditions.
Safe Usage: How to Add Baking Soda to Your Routine
If you’re considering baking soda for health purposes, it’s important to approach it with caution. Start with a small amount—about 1/8 teaspoon mixed in water—and take it on an empty stomach. You can gradually increase to 1/4 teaspoon, but it’s always a good idea to consult with a healthcare provider first.
Make sure to time your intake correctly, taking it at least an hour before or after meals. This prevents any potential interference with digestion. Keep in mind that while baking soda has shown promising effects in some studies, it is not a substitute for medical treatment, and it’s important to remember that no approved therapeutic claim has been made regarding its use for autoimmune conditions.
Also, be mindful of how your body reacts. Baking soda can affect sodium levels, so if you notice anything unusual like shortness of breath or a fast heartbeat, stop using it and consult your doctor.
The Science Behind Baking Soda and Kidney Health
Beyond its potential for helping with autoimmune conditions, baking soda has also been studied for its role in kidney health. In cases of chronic kidney disease, the kidneys struggle to filter waste, leading to a buildup of acid in the body. Doctors have used baking soda to help balance this acid and reduce the workload on the kidneys.
In one study, researchers noticed that baking soda lowered inflammation in both rats with kidney disease and healthy rats. This shift in inflammation suggests that baking soda might help improve kidney function by reducing harmful immune responses. While these findings are promising, they highlight how baking soda’s effects go beyond just one part of the body—it may help reduce inflammation in multiple areas.
If you’re interested in using baking soda for health benefits, it’s essential to remember that its effects are still being explored. Always talk to a healthcare provider before making it part of your routine, especially if you have existing conditions like kidney disease.
Baking Soda’s Place in Managing Inflammation

Baking soda is a common household item with some surprising potential when it comes to health, especially in managing inflammation related to autoimmune diseases and kidney function. While its use for conditions like rheumatoid arthritis or kidney disease is still being studied, the science behind how it interacts with the immune system is intriguing.
That said, baking soda should be viewed as a helpful tool, not a replacement for medical treatment. Its simplicity and availability make it a convenient option to explore, but it’s essential to approach it with care. If you’re considering incorporating it into your routine, discussing it with a healthcare professional is always the best step forward.