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	Comments on: Scientists Discovered How to Kill Prostate Cancer Cells Without Harming Healthy Tissue — Here&#8217;s the Breakthrough	</title>
	<atom:link href="https://fitfoundme.com/scientists-have-discovered-a-method-to-destroy-prostate-cancer-by-targeting-a-single-enzyme-without-harming-healthy-cells/feed/" rel="self" type="application/rss+xml" />
	<link>https://fitfoundme.com/scientists-have-discovered-a-method-to-destroy-prostate-cancer-by-targeting-a-single-enzyme-without-harming-healthy-cells/</link>
	<description>Healthy Living</description>
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		By: HERB		</title>
		<link>https://fitfoundme.com/scientists-have-discovered-a-method-to-destroy-prostate-cancer-by-targeting-a-single-enzyme-without-harming-healthy-cells/comment-page-1/#comment-39761</link>

		<dc:creator><![CDATA[HERB]]></dc:creator>
		<pubDate>Mon, 17 Nov 2025 14:57:32 +0000</pubDate>
		<guid isPermaLink="false">https://fitfoundme.com/?p=33879#comment-39761</guid>

					<description><![CDATA[So what’s really happening in cancer?
- Many cancers do involve DNA mutations — especially in p53, KRAS, BRCA1/2, etc.
- But epigenetic dysregulation is increasingly recognized as a co-conspirator:
- Silencing tumor suppressors via methylation
- Activating oncogenes via histone acetylation
- Reprogramming metabolic genes to support lipid synthesis, like PI5P4Kα
🧪 In context of lipid metabolism:
The article’s pivot to PI5P4Kα and lipid metabolism suggests a metabolic reprogramming layer — often driven by:
- Epigenetic control of metabolic enzymes
- Non-mutational adaptation to support rapid growth
So yes — the “DNA mutation” quip is a simplification. The real story includes epigenetic misexpression, metabolic rewiring, and non-genetic plasticity that cancer cells exploit.

Epigenetic is not genetic. There is a difference. To treat diseases as being the wrong thing is a waste of time and lives. Cancer is largely epigenetic-rooted in cause, not in the lesser way of genetic DNA mutation. 

As a sidebar, did you the over 100 autoimmunse diseases are from proper gene expression going off-kilter? If science would correct this instead just suppressing the human immune system to keep from attack its own body housing it, the side effects like cancer and raging infections would go away. But no.]]></description>
			<content:encoded><![CDATA[<p>So what’s really happening in cancer?<br />
&#8211; Many cancers do involve DNA mutations — especially in p53, KRAS, BRCA1/2, etc.<br />
&#8211; But epigenetic dysregulation is increasingly recognized as a co-conspirator:<br />
&#8211; Silencing tumor suppressors via methylation<br />
&#8211; Activating oncogenes via histone acetylation<br />
&#8211; Reprogramming metabolic genes to support lipid synthesis, like PI5P4Kα<br />
🧪 In context of lipid metabolism:<br />
The article’s pivot to PI5P4Kα and lipid metabolism suggests a metabolic reprogramming layer — often driven by:<br />
&#8211; Epigenetic control of metabolic enzymes<br />
&#8211; Non-mutational adaptation to support rapid growth<br />
So yes — the “DNA mutation” quip is a simplification. The real story includes epigenetic misexpression, metabolic rewiring, and non-genetic plasticity that cancer cells exploit.</p>
<p>Epigenetic is not genetic. There is a difference. To treat diseases as being the wrong thing is a waste of time and lives. Cancer is largely epigenetic-rooted in cause, not in the lesser way of genetic DNA mutation. </p>
<p>As a sidebar, did you the over 100 autoimmunse diseases are from proper gene expression going off-kilter? If science would correct this instead just suppressing the human immune system to keep from attack its own body housing it, the side effects like cancer and raging infections would go away. But no.</p>
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